Cover of: The role of prostaglandins in the utero-ovarian axis of the cycling and early pregnant mare | Michael Walter Vernon

The role of prostaglandins in the utero-ovarian axis of the cycling and early pregnant mare

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Endometrial strips collected from pregnant and non-pregnant pony mares were incubated for 2 h at 37 deg C. With PGF measured by radioimmunoassay, endometrial PGF content and production increased from the early stages of the oestrous cycle until and then declined.

Thus, max. concentrations occurred at the expected time of luteolysis. In pregnant females, PGF content and production Cited by: 4. THE ROLE OF PROSTAGLANDINS IN THE UTERO-OVARIAN AXIS OF THE CYCLING AND EARLY PREGNANT MARE By Michael Walter Vernon June, Chairman: Dr. Daniel C. Sharp Major Department: Animal Science The interrelationships between the equine ovary and uterine prostaglandins were studied.

Since little is known. The role of prostaglandins in the utero-ovarian axis of the cycling and early pregnant mare / By Michael Walter Vernon. Topics: Animal Science, Animal Science thesis Ph. D, Dissertations, Academic, Horses, Physiological effect, Prostaglandins, Reproduction, UFCited by: 4.

PROSTAGLANDINS PROSTAGLANDIN F CONCENTRATIONS IN UTERO-OVARIAN VEIN PLASMA OF PREPUBERAL AND MATURE GILTS George B. Rampacekl, Robert R. Kraeling2, Terry E.

Kiserl, C. Richard Barb2 and L. Benyshekl 1Department of Animal and Dairy Science, University of Georgia and 2Richard B. Russell Research Center, SEA, USDA, Athens, Georgia ABSTRACT Prostaglandin Cited by: Prostaglandins are also inti­ mately involved in the mechanism of menstruation. More detailed understanding of this role should lead to more effective treatments for menorrhagia and dysmenorrhoea.

These substances also playa part in the mechanism of implantation, and further research in this area may lead to more effective therapy for infertility. Secretion of Prostaglandin F 2 a in Cycling and Pregnant Ewes.

the utero-ovarian vein (cycling ewes) with special emphasis on the role of prostaglandin F2α (PGF2α) in. Prostaglandins and Male Reproductive Physiology.

Rodney W. Kelly. Medical Research Council Human Reproductive Science Unit, University of Edinburgh Centre for Reproductive Biology, 37 Chalmers Street, Edinburgh EH3 9ET, UK. Book Editor(s): Peter Curtis‐Prior. prostaglandin peak with rupture of the chorioallan-tois (“water breaking”) and expulsion of the fetus.8,9 3.

Evidence-Based Applied Endocrinology and Practical Therapeutics Progestogen supplementation can be used as treat-ment for early-bred or known pregnant mares if the mare’s endogenous progesterone production is sus. Vernon, M.W.,The role of prostaglandins in the utero-ovarian axis of the cycling and early pregnant mare, Ph.D.

dissertation, University of Florida, Gainesville. Google Scholar. Vernon MW: The role of prostaglandins in the utero- ovarian axis of the cycling and early pregnant mare. PhD Disserta- tion. Univ. of Florida, Gainesville, Winer BJ: Statistica/ Princip/es in Experimenta/ Design, McGraw Hill, New York, NY:Woodley SL, Burns PJ, Douglas RH, Oxender WD: Pro- longed interovulatory.

Synthetic prostaglandins are sometimes used to induce labor for pregnant women. Potential Problems with Prostaglandins.

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Problems with prostaglandins production can occur, leading to unwanted inflammation in the body. The prostaglandins are part of a natural response to stresses, but excessive prostaglandins production can cause chronic problems.

Blatchley FR, Donovan BT, Poyser NL, Horton EW, Thompson CJ, Los M. Identification of prostaglandin F2-alpha in the utero-ovarian blood of guinea-pig after treatment with oestrogen.

Nature. Mar 26; ()– Challis JR, Heap RB, Illingworth DV. Concentrations of oestrogen and progesterone in the plasma of non-pregnant, pregnant. Prostaglandins are a group of endogenously occurring acidic lipids that appear to be involved in a large number of reproductive processes.

Kurzrok and Leib first reported that a substance in human semen altered the contractile activity of human uterine strips.

1 InVon Euler named this substance prostaglandin because he believed that it was produced in the prostate gland; however, it was. Prostaglandin release from pregnant uteri Extracts of samples of the fluid bathing uteri from pregnant rats contained prostaglandin-like activity.

This did not exactly match prostaglandin E2 or F2a in that several of the extracts caused relaxation of the chick rectum, an effect only rarely seen and to a lesser extent with F2a. Thin layer. -Utero-ovarian vein and ovarian artery are in close apposition -Bursas (cow not mare) 1.

Is she pregnant. If yes job done. Is she cycling. - stage of cycle - estrus = toned uterus + cervix for cows, flaccid for mares Prostaglandins in Mare Programs-Induce estrus at known time.

If a women is a few days pregnant then the endometriosis implants producing prostaglandin F would incorrectly signal the ovary to start a new menstrual cycle, causing the womb lining with the implanted egg to be expelled - and the consequence is an early miscarriage.

Prostaglandins also play an important role in the contractions of womb and. In the early pregnant mare, PGF production increased during the first 16 days of pregnancy in a pattern similar to that of the nonpregnant mare; how- ever, concentrations of PGF continued to.

Tuvemo T. Role of prostaglandins, prostacyclin, and thromboxanes in the control of the umbilical-placental circulation. Semin Perinatol ; Rankin JHG, Phernetton TM. Circulatory responses of the near-term sheep fetus to prostaglandin E2.

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Am J Physiol ; Terragno NA, Terragno A, McGiff JC. Role of prostaglandins in. Spontaneous prolongation of the luteal phase has been described in horses, but the underlying causes are still unclear. The present study investigated details of gonadotrophin and progestogen secretion in pregnant mares (n = 11) with or without experimentally reduced early postovulatory luteal function.

From days 0 to 3 after ovulation, they were treated with the prostaglandin F2α (PGF2. - Certain prostaglandins are involved with the introduction of labour and other reproductive processes, and the role of fertility. PGE2 causes uterine contractions and has been used to induce labour.

- They are involved in several other organs and systems such as the gastrointestinal tract, cell growth and the immune system response. On the contrary, prostaglandins (PGs) are known to play a key role in the maintenance of human pregnancy and the onset of labour, whereas their possible role in regulation of uterine contractility in non-pregnant uteri is still enigmatic.

The use of advanced reproductive endocrinology can generate important economic benefits for equine breeding farms. Pregnancy in the mare involves considerable endocrine changes, which can be explained in part by the development of different structures such as embryonic vesicles, primary and secondary CL, endometrial cups and development of fetoplacental units.

Cardiac output and uteroplacental blood flow (UPBF) were measured using radiolabeled microspheres. Prostaglandin E (PGE) concentration was measured by radioimmunoassay in the uterine vein and peripheral artery of the pregnant nephrectomized rabbit.

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Either meclofenamate or indomethacin 2 mg/kg were utilized to inhibit prostaglandin synthesis. Since ovulation can occur during P&E therapy, a dose of prostaglandin or prostaglandin analog is added to the therapy on the final day of treatment.

This day protocol leaves ovaries with a cohort of mm follicles that will begin maturation, deviation. ©— Bioethics Research Library Box Washington DC Induction of labour is offered to pregnant women when it is thought the outcome will be better for the mother and/or baby if the baby is born than if the pregnancy continues.

Common reasons include prolonged pregnancy, prelabour rupture of the membranes, concerns about the health of the mother such as pre-eclampsia or the baby such as poor growth.

The concentrations of prostaglandins E 2 and F α were measured by radioimmunoassay in samples of endometrial tissue from women. The results showed that the concentration of prostaglandin E 2 (ng/ mg of wet tissue; mean ± SD) in tissue from apparently healthy women with regular menstrual cycles was 793 ± 99 during the menstrual period.

The level in the proliferative and early. Prostaglandins E, and F2a were used in these experiments. Their formulae are shown in Fig. Virgin female guinea-pigs of g and rats of g were used, and the uterine horns were studied in dioestrous or under the influence of oestrogens when the animals were in natural oestrus.

Prostaglandin can be synthesized and released from the blind ending uterine horn, just as is produced by a normally connected uterine horn. In those with a local utero-ovarian pathway for luteolysis, such as the cow, the absence of a segment of the uterus could result in insufficient PGF 2α to cause regression of the corpus luteum.

The role of prostaglandins in the utero-ovarian axis of the cycling and early pregnant mare / View Metadata. By: Vernon, Michael Walter, Archives and Rare Book Library () Subjects: GEU Physiological effect Southern imprint Tobacco Tobacco use Virginia.

Estrus cycle is a rhythmic change that occur in the reproductive system of females starting from one estrus phase to another. The normal duration of estrus cycle is 21 days in cow, sow, and mare, 17 days in ewe, and 20 days in doe.

The species which exhibit a single estrus cycle are known as monstrous and species which come into estrus twice or more are termed polyestrous animals.The involvement of prostaglandins (PG) in the vasopressin (VP) action on the human uterus was investigated in healthy women during three menstruations.

The uterus, also known as the womb, is an about 8 cm long hollow muscular organ in the female pelvis and lies dorsocranially on the consists of several anatomical parts, such as the cervix, isthmus, and body.

While its anatomy sounds simple, its histology is more complicated. It consists of three major layers, but the exact histological structure depends upon the state - if it is in.