Evolution of meningococcal disease

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  • English

CRC Press , Boca Raton, Fla
Meningitis, Cerebrospinal., Meningitis, Cerebrospinal -- Epidemiology., Meningitis, Meningococcal -- occurr
Statementeditor, Neylan A. Vedros.
ContributionsVedros, Neylan A., 1929-
LC ClassificationsRC124 .E95 1987
The Physical Object
Pagination2 v. :
ID Numbers
Open LibraryOL2389199M
ISBN 100849346436, 0849346444, 0849346452
LC Control Number87018406

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Invasive meningococcal disease (IMD) is a condition, too often fatal, caused by invasion of the bacterium Neisseria meningitidis into the blood stream and subsequent development of septic shock and purpura fulminans in a subset of patients. When the bacterium gains access to the central nervous system, meningitis by: Epidemic disease caused by Neisseria meningitidis, the meningococcus, has been recognised for two centuries, but remains incompletely controlled and have been dramatic reductions in serogroup A and C meningococcal disease following the introduction of protein-polysaccharide conjugate vaccines but there is currently no comprehensive vaccine against Cited by:   Meningococcal disease occurs worldwide with incidence rates varying from 1 to cases perThe causative organism, Neisseria meningitidis, is an obligate commensal of humans, which normally colonizes the mucosa of the upper respiratory tract without causing invasive disease, a phenomenon known as s using molecular methods Cited by: Meningococcal disease is an acute, potentially severe illness caused by the bacterium Neisseria meningitidis.

Illness believed to be meningococcal disease was first reported in the 16th century. The first definitive description of the disease was by Vieusseux in Switzerland in The bacterium was first identified in the spinal fluid of. Meningococcal disease generally occurs 1–10 days after exposure and presents as meningitis in ≥50% of cases.

Meningococcal meningitis is characterized by sudden onset of headache, fever, and stiffness of the neck, sometimes accompanied. Meningococcal meningitis, the most common presentation of meningococcal disease, “should always be viewed as a medical emergency” and requires admission Evolution of meningococcal disease book a hospital, according to the World Health Organization.

In the United States, between 1, and 2, cases of meningococcal disease occur each year. Licensed vaccines against meningococcal disease have been available for more than 40 years. Over time, there have been major improvements in strain coverage and vaccine availability, but to date no universal vaccine against meningococcal disease exists.

Vaccines are serogroup specific and confer varying degrees of duration of protection. Meningococcal disease is a major public health problem and immunization is considered the best strategy Evolution of meningococcal disease book prevention.

The introduction of meningococcal C. Meningococcal disease describes infections caused by the bacterium Neisseria meningitidis (also termed meningococcus). It has a high mortality rate if untreated but is best known as a cause of meningitis, it can also result in sepsis, which is an even more damaging and dangerous itis and meningococcemia are major causes of illness, death, Specialty: Infectious disease, critical care medicine.

Overall, the evolution of novel meningococcal vaccines and the effective implementation of targeted vaccination programs has led to a substantial decrease. Infectious agent of meningococcal disease Neisseria meningitidis (or meningococcus) is a gram-negative diplococcus.

Description Evolution of meningococcal disease EPUB

There are 13 serogroups of N. meningitidis, with 6 serogroups (A, B, C, W, X and Y) accounting for the majority of cases of invasive meningococcal disease (IMD) worldwide. Serogroup B is currently responsible for most IMD cases.

Find many great new & used options and get the best deals for Evolution of Meningococcal Disease by Vedros, Neyland at the best online prices at eBay. Free shipping for many products. Meningococcal disease is caused by bacteria called Neisseria meningitidis.

It can lead to serious blood infections. When the linings of the brain and spinal cord become infected, it is called meningitis.

The disease strikes quickly and can have serious complications, including death. Anyone can get meningococcal disease. Abstract. Neisseria meningitidis is a leading cause of bacterial meningitis and other serious infections worldwide.

The epidemiological profile of N. meningitidis is highly changeable, with great differences in disease incidence and serogroup distribution. Six serogroups (namely serogroups A, B, C, W, X, and Y) are responsible for most cases of Cited by: The overall case-fatality rate for meningococcal disease is 10% to 15% and is somewhat higher in adolescents.

Death is more common in those with coma, hypotension, leukopenia, and thrombocytopenia and among those who do not have meningitis.

Meningococcal Infections Figure 7 from Meningococcal Infections in Red Book. Meningococcal septicemia and meningitis continue to be important causes of devastating illness, death, and long-term disability in both developed and resource-poor countries of the world.

Few diseases have attracted as much public attention, or are as feared by parents and family members, as well as the medical staff who have to care for affected patients. Meningococcemia is a rare infectious disease characterized by upper respiratory tract infection, fever, skin rash and lesions, eye and ear problems, and possibly a sudden state of extreme physical depression (shock) which may be life-threatening without appropriate medical care.

Invasive meningococcal disease is caused by a bacteria called Neisseria meningitidis and typically manifests as a blood infection, meningitis, or both.

Symptoms may include sudden onset of fever, headache, rash, limb pain, stiff neck, nausea, vomiting, photophobia (eyes being more sensitive to light), and altered mental status (confusion). Meningococcal disease is a life-threatening infection.

It is a term used to describe two major illnesses, meningitis and septicaemia (blood poisoning). Men B is the most common strain in the UK but other strains include Men A, Men C, Men W and Men Y. Meningitis Now offer support for anyone affected. Infectious disease, in medicine, a process caused by an agent, often a type of microorganism, that impairs a person’s many cases, infectious disease can be spread from person to person, either directly (e.g., via skin contact) or indirectly (e.g., via contaminated food or water).

An infectious disease can differ from simple infection, which is the invasion of and replication in. Meningococcal bacteria are only passed from person to person by regular close, prolonged household or intimate contact with infected secretions from the back of the nose and throat.

Meningococcal disease is uncommon but serious. It usually takes the form of a blood infection (septicaemia) or infection of the membranes covering the brain and. Meningococcal Disease. What is meningococcal disease.

Meningococcal disease is caused by bacteria called Neisseria meningitidis. It can lead to serious blood infections.

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When the linings of the brain and spinal cord become infected, it is called meningitis. The disease strikes quickly and can have serious complications, including Size: 51KB. For more information on meningococcal vaccines for those travelling abroad, see the meningococcal disease health information sheet on the National Travel Health Network and Centre (NaTHNaC.

Meningitis is the most common form of meningococcal infection, accounting for about 75% of cases. Septicemia is the next common – 20% of cases – and the other infections make up the balance. All forms of meningococcal disease are medical emergencies and require immediate medical attention.

Meningococcal disease is spread from close and prolonged contact with an infected person through saliva or secretions (fluids) from the nose and throat.

Examples include kissing, sneezing or coughing, living in close quarters with an infected person, sharing eating or drinking utensils. meningococcal disease are sporadic; however, outbreaks of meningococcal disease do occur. Etiologic agent Neisseria meningitidis is a gram-negative diplococcal bacterium.

Approximatelycases of meningococcal disease occur annually in the United States, a rate of /, Size: KB. This systemic form of the disease, meningococcemia, usually precedes the development of meningococcal meningitis by hours.

Meningococcemia is characterized by severe, widespread vascular injury, with evidence of circulatory collapse and disseminated intravascular coagulation (DIC) Skin rashes occur in about half of all individuals with.

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A baby has died after contracting an unidentified strain of the meningococcal disease in Darwin on the weekend, but authorities don’t believe it’s connected to an outbreak in Central Australia.

Handbook of Meningococcal Disease: Infection Biology, Vaccination, Clinical Management Matthias Frosch (Editor), Martin C. Maiden (Editor) ISBN: November Wiley-Blackwell Pages.

Evidence of ongoing evolution, international transmission, and strain replacement stresses the importance of maintaining N. meningitidis surveillance in Africa following the MACV implementation. IMPORTANCE Meningococcal disease (meningitis and bloodstream infections) threatens millions of people across the meningitis belt of sub-Saharan by: It can be used for travelers going to areas where meningococcal disease is more common or is epidemic.

In the early s, the vaccine has been suggested for use in incoming college freshmen, particularly those living in dormitories. These students appear to have a somewhat higher risk of meningococcal infections.Meningococcal Disease (Neisseria meningitidis) Case Definition Recommend on Facebook Tweet Share Compartir NOTE: A surveillance case definition is a set of uniform criteria used to define a disease for public health surveillance.